Design of a gastroretentive mucoadhesive dosage form of furosemide for controlled release
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چکیده
منابع مشابه
A Mucoadhesive Gastroretentive Dosage Form for Valacyclovir
Objective: The objective of the present work was to formulate a gastroretentive dosage form of Valacyclovir, an anti viral drug. Methods: Valacyclovir gastroretentive mucoadhesive tablets were prepared using polymers such as Carbopol 974P and hydroxy propyl methyl cellulose (HPMC) K4M, in different proportions by wet granulation technique. Compatibility studies were performed by FTIR spectrosco...
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deployable scissor type structures are composed of the so-called scissor-like elements (sles), which are connected to each other at an intermediate point through a pivotal connection and allow them to be folded into a compact bundle for storage or transport. several sles are connected to each other in order to form units with regular polygonal plan views. the sides and radii of the polygons are...
Furosemide pharmacokinetics and pharmacodynamics following gastroretentive dosage form administration to healthy volunteers.
The objective of this study was to evaluate the pharmacokinetic and pharmacodynamic properties of furosemide following gastroretentive dosage from (GRDF) administration. A furosemide (60 mg) GRDF, releasing the drug during 6 hours in vitro, or an immediate-release tablet was administered to healthy male volunteers (N = 14) in a crossover design. Food and liquid intake were standardized; urine w...
متن کاملDevelopment and Evaluation of Thymol Microparticles Using Cellulose Derivatives as Controlled Release Dosage Form
Thymol, an important and advantageous component of many essential oils, has been applied as an antimicrobial agent in animals. To increase the duration of action of this compound in ruminants, it was decided here to prepare a controlled release carrier for thymol. Hydroxy propyl methyl cellulose (HPMC) and ethyl cellulose (EC) were used as the matrix polymer here. Mixtures of thymol with eight ...
متن کاملDevelopment and Evaluation of Thymol Microparticles Using Cellulose Derivatives as Controlled Release Dosage Form
Thymol, an important and advantageous component of many essential oils, has been applied as an antimicrobial agent in animals. To increase the duration of action of this compound in ruminants, it was decided here to prepare a controlled release carrier for thymol. Hydroxy propyl methyl cellulose (HPMC) and ethyl cellulose (EC) were used as the matrix polymer here. Mixtures of thymol with eight ...
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ژورنال
عنوان ژورنال: Acta Pharmaceutica Sinica B
سال: 2012
ISSN: 2211-3835
DOI: 10.1016/j.apsb.2012.05.004